Acute pain. Acute pain
Conditions
Interventions
Intervention 1: In intervention group, 300 mg pregabalin is administered orally as an analgesic, 2 hours before surgery. Intervention 2: In control group placebo (a capsule similar to the drug without
Treatment - Drugs
In intervention group, 300 mg pregabalin is administered orally as an analgesic, 2 hours before surgery
In control group placebo (a capsule similar to the drug without any effective substance) is administered.
Sponsors
Vice chancellor for research, Kerman University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: Patients, who are admitted for thoracic surgery, age 20 to 65 year. Exclusion criteria: pregnancy, history of allergy to pregabalin, history of treatment with pregabalin or gabapentin, history of chronic pain syndromes and painkiller consumption, addiction to alcohol or drugs, allergy to pethidine, psychiatric drug consumption, surgery lasting more than 4 hours, uncontrolled blood pressure, history of convulsion and the patients who had preoperative pain based on the visual analogue scale (VAS) had preoperative pain.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: At the end of operation and transferring to recovery room, the score of pain is measured every 15 minutes for an hour and after transporting to ward, every 4 hours for 24 hours. Method of measurement: VISUAL ANALOGUE SCALE. | — |
Secondary
| Measure | Time frame |
|---|---|
| The dose of analgesic. Timepoint: during and after surgery. Method of measurement: recording the dose and frequency of administration. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHosein Sattari
Kerman University of Medical Sciences
Outcome results
None listed