Breast malignancy. Malignant neoplasm of breast
Conditions
Interventions
Intervention 1: Using Scalp Cooling Cap 30 minutes before, during and up to 2.5 hours after chemotherapy with "Adriamycin and Cyclophosphamide" in breast cancer. Intervention 2: Using Scalp Cooling Ca
Sponsors
Vice chancellor for research, Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: consent for using the cap and filling on the questionnaire using chemotherapy regimens resulting in total alopecia including: 1. Doxorobicin plus cyclophosphamide followed by one of the Taxane drugs (in one, two or three-week regimens) 2. BEP regimen in gonadal malignanciy 3. FEC (5Fu-Epirubicin -cyclophosphamaid) regimen 4. VAC (vincristin-Doxorobicin -cyclophosphamaid) regimen in sarcomas performance higher than 70% age between 18 to 75 years
Exclusion criteria
Exclusion criteria: Melanoma Blood malignancies Liver or kidney dysfunction Migraine History of cryoglobulinemia Systemic lupus erythematosus No consent for using the caps
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Alopecia. Timepoint: prior to each chemotherapy cycle. Method of measurement: visual inspection and questionnaire based on WHO alopecia grading. | — |
Secondary
| Measure | Time frame |
|---|---|
| Headache. Timepoint: following every cycle of chemotherapy. Method of measurement: qestionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMitra Fazl Ersi
Mashhad University of Medical Sciences
Outcome results
None listed