Clinical trial of evaluation of pain control in orthopaedic surgery after adding magnesium sulfate to fentanyl infusion. Diseases of the musculoskeletal system and connective tissue
Conditions
Interventions
Intervention 1: Group 1 (magnesium sulfate ) 40 patients, we infused fentanyl plus magnesium sulfate in ordered below: 30mg/kg sulfate magnesium in 250 cc sodium chloride (over 10 minute) and then 10
Treatment - Drugs
Group 1 (magnesium sulfate ) 40 patients, we infused fentanyl plus magnesium sulfate in ordered below: 30mg/kg sulfate magnesium in 250 cc sodium chloride (over 10 minute) and then 10 mg/kg for 48 hou
In control group (40 patients) we infused the 250cc sodium chroride over 10 minutes and then the equal volume of magnesium sulfate were infused.
Sponsors
Vice chancellor for research , Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria : patients with the age group of 20 to 50 years? patients with ASA I, II , orthopedic surgery will be done under the same procedure with General anesthesia and the surgical team are the same . Exclusion criteria : Patients who have major disease of liver? kidney? cardiovascular? asthma and COPD ? patients were treated with calcium channel blocker.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: 1 , 6 , 12 , 18 , 24 , 48. Method of measurement: Visual analogue scale (VAS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Sedation. Timepoint: First and 1,6,12,18,24,48 hours later. Method of measurement: Ramsay score. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactKarim Hemati
Iran University of Medical Sciences
Outcome results
None listed