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Effect of oral ketamine versus placebo on pain relief in patients with renal colic

Effect of oral ketamine versus placebo on pain relief in patients with renal colic: a double blinded randomized clinical trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201410319014N46
Enrollment
44
Registered
2014-11-01
Start date
2013-04-26
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal colic. Unspecified renal colic

Interventions

Intervention 1: Intramuscular injection of pethidine 1 mg/kg to maximum of 100 mg plus a single dose of 5 mg/kg oral ketamine 0.5%. Intervention 2: Intramuscular injection of pethidine 1 mg/kg to maxi
Treatment - Drugs
Placebo
Intramuscular injection of pethidine 1 mg/kg to maximum of 100 mg plus a single dose of 5 mg/kg oral ketamine 0.5%
Intramuscular injection of pethidine 1 mg/kg to maximum of 100 mg plus a single dose of 0.1 mg/kg oral glucose 5%.

Sponsors

Vice-chancellor for Research the Technology, Hamadan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: (a) having renal colic; (b) age of 18 to 60 years. Exclusion criteria: (a) having psychological or personality disorder; (b) pregnancy or breastfeeding; (c) having cardiovascular diseases, hypertension, epilepsy, glaucoma, or diabetes.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Severity of pain. Timepoint: before and 3 hours after intervention. Method of measurement: using Visual Analog Scale.

Secondary

MeasureTime frame
Severity of nausea. Timepoint: before and 3 hours after intervention. Method of measurement: using Four Point Scale.;Number of vomiting. Timepoint: before and 3 hours after intervention. Method of measurement: with question.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaedeh Hassani

Shahid Beheshti Hospital

msh6440@gmai.com+81 38380704

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026