Effect of oral Theophylline on chronic obstructive pulmonary disease

Comparison of oral Theophylline with Atorvastatin in reduction of serum CRP levels in patients with chronic obstructive pulmonary disease

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014102919747N1

Enrollment

100

Registered

2014-11-24

Start date

2014-10-19

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic obstructive pulmonary disease. Chronic obstructive pulmonary disease, unspecified

Interventions

Intervention 1: Theophylline group: tablet theophylline 200 mg(made in Dr Abidi company) every 12 hours for 2 weeks. Intervention 2: Atorvastatin group: tablet atorvastatin 10 mg( made in Dr Abidi com

Treatment - Drugs

Placebo

Theophylline group: tablet theophylline 200 mg(made in Dr Abidi company) every 12 hours for 2 weeks

Atorvastatin group: tablet atorvastatin 10 mg( made in Dr Abidi company) every 12 hours for 2 weeks

Placebo group: tablet placebo 200 mg every 12 hours for 2 weeks

Eligibility

Sex/Gender

All

Age

40 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:Having age between 40 to 70 years old? Having no other background diseases that change the level of CRP like infectious? rheumatologic? malignancy diseases? Lack of consumption of other drugs? Satisfaction for taking part in study. Exclusion criteria: Observation of side effect of drugs during the study? Dissatisfaction of patients in every stage of study? Consumption of other drugs at the same time.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
CRP. Timepoint: before intervention and two weeks after intervention. Method of measurement: Latex Agglutinasition test.	—

Secondary

Measure	Time frame
CAT score. Timepoint: before intervention and two weeks after intervention. Method of measurement: CAT test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSiamak Lotfi

Ardebil University of Medical Science

s_siamak_lotfi@yahoo.com+98 45 3351 8663

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026