Atrophy Vaginal inpost menopausal women. Postmenopausal Atrophic Vaginitis
Conditions
Interventions
Intervention 1: fennel 7% vaginal cream one applicator once a day for 8 week. Intervention 2: placebo,vaginal cream,once a day for 8 week.
Treatment - Drugs
Placebo
fennel 7% vaginal cream one applicator once a day for 8 week
placebo,vaginal cream,once a day for 8 week.
Sponsors
Vice chancellor for research, Ahvaz JundiShapur University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
45 Years to 65 Years
Inclusion criteria
Inclusion criteria: inclusion criteria: Age between 45 to 65, Amenorrhea at less 12 month or have hormone test with FSH level more than 40 unit, Presenting symptom of vaginal atrophy, Have Sexual activity and single partner? Exclusion criteria: Vaginal infection, Genital Abnormalities, The use of Sex Hormones within the 8 weeks preceding study, user of smoke and alcohol and etc ? Genital Bleeding or spotting of unknown Cause, Use of Phytoestrogens such as Soy, Red clover, Fenugreek, Vitex within the last one Month
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vaginal Atrophy. Timepoint: Before intervention, Two weeks after the intervention, Four weeks after intervention, Eight weeks after intervention. Method of measurement: Kupperman Index Questionnaire.;Percentage of Maturity vaginal cells. Timepoint: Before and after eight weeks (end of intervention). Method of measurement: Vaginal smear.;Vaginal PH. Timepoint: Before and after eight weeks (end of intervention). Method of measurement: By PH meter strips. | — |
Secondary
| Measure | Time frame |
|---|---|
| Dyspareunia. Timepoint: Before intervention, Two weeks after the intervention, Four weeks after intervention, Eight weeks after intervention. Method of measurement: self-assessed 4-point scale of composite score.;Added at 2015-08-03: menopausal symptoms. Timepoint: Added at 2015-08-03: Before intervention, 2, 4, 8 weeks after intervention. Method of measurement: Added at 2015-08-03: Kupperman Index Questionnaire.;Added at 2015-08-03: Temperament. Timepoint: Added at 2015-08-03: Before and after intervention. Method of measurement: Added at 2015-08-03: Temperament questionnaires.;Added at 2015-08-03: severity of menopausal symptoms. Timepoint: Added at 2015-08-03: Before intervention, 2, 4, 8 weeks after intervention. Method of measurement: Added at 2015-08-03: Menopause Rating Scale (MRS) questionnaire.;Added at 2015-08-03: Sexual function. Timepoint: Added at 2015-08-03: Before and after intervention. Method of measurement: Added at 2015-08-03: Female Sexual Function Index (FSFI) questionnaire.;Added at 2015-08-03: Sexual satisfaction. Timepoint: Added at 2015-08-03: Before and after intervention. Method of measurement: Added at 2015-08-03: Larson's sexual satisfaction questioner. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMasumeh yaralizadeh
Ahvaz Jundishapur University of Medical Sciences
Outcome results
None listed