Skip to content

Effect of single dose Phenobarbital on treatment of term and near term newborn'shyper bilirubinemia admitted in the hospital

Effect of single dose Phenobarbital on treatment of term and near term newborn'shyper bilirubinemia admitted in the hospital

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014102919716N4
Enrollment
30
Registered
2015-03-15
Start date
2014-11-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Near term newborn's hyper bilirubinemia. Neonatal jaundice, unspecified

Interventions

Intervention 1: In the intervention group babies receive phenobarbital with phototherapy. Phenobarbital with dose (12 mg / kg) administered orally in one dose. Indication of starting and discontinuin
Treatment - Drugs
In the intervention group babies receive phenobarbital with phototherapy. Phenobarbital with dose (12 mg / kg) administered orally in one dose. Indication of starting and discontinuing phototherapy w
Control group give only phototherapy,without phenobarbital

Sponsors

North Khorasan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Days to 7 Days

Inclusion criteria

Inclusion criteria: Term and near-term babies (> 35 week) or (> 2500 g) with serum bilirubin levels in the therapeutic range (> 15 mg / dl) who admitted in hospital without signs of hemolysis, internal bleeding, G6PD, sepsis, severe respiratory illness requiring mechanical ventilation and congenital anomalies are enrolled after parental consent.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Serum bilirubin. Timepoint: Weeks 35-42. Method of measurement: Blood sample test.;Hematocrit,coombs,blood group,retic count. Timepoint: at birth time and starting treatment to discharge at hospital. Method of measurement: serum examination.

Secondary

MeasureTime frame
Hospitalization period, phototherapy duration. Timepoint: Days of hospitalization, hours of phototherapy. Method of measurement: Medical records.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Ghasem Bayani

North Khorasan University of Medical Sciences

bayani.ghasem@yahoo.com+98 58 4221 1008

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026