Comparison of dexmedetomidine versus remifentanil on rate of discharge from recovery in patients candidate for posterior lumbar spine fusion surgery

Comparison of the effects of dexmedetomidine and propofol versus remifentanil and propofol on rate of discharge from recovery in patients candidate for posterior lumbar spine fusion surgery

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014102819715N1

Enrollment

Registered

2014-12-24

Start date

2014-12-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fusion of spine. Other specified deforming dorsopathies

Interventions

Intervention 1: Intervention 1. Dexmedetomidine, 0.1 µg/kg, intravenous. Intervention 2: Intervention 2. Remifentanil, 1 µg/kg, intravenous.

Treatment - Drugs

Intervention 1. Dexmedetomidine, 0.1 µg/kg, intravenous.

Intervention 2. Remifentanil, 1 µg/kg, intravenous.

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patient satisfaction; Age between 18-65 years old; Patients candidate for posterior lumbar spine fusion surgery; Elective surgery; No history of spinal surgery. Exclusion criteria: Addiction to drugs or alcohol; Sensitivity to drugs use in this study; Long-term and chronic use of painkillers; Respiratory and cardiovascular diseases; Unpredictable events such as severe bleeding.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Activity level. Timepoint: Every ten minutes after extubation. Method of measurement: Aldrete score.;Respiration. Timepoint: Every ten minutes after extubation. Method of measurement: Aldrete score.;Consciousness. Timepoint: Every ten minutes after extubation. Method of measurement: Aldrete score.	—

Secondary

Measure	Time frame
Blood pressure. Timepoint: Every ten minutes after extubation. Method of measurement: Sphygmometer.;O2 saturation. Timepoint: Every ten minutes after extubation. Method of measurement: Pulse oximeter.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactArash Pourbakhshandeh

Iran University of Medical Sciences

Dr.pourbakhshandeh@gmail.com+98 21 6435 2326

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026