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The effect of probiotics on enteral milk tolerance and prevention of Necrotizing Enterocolitis in preterm infants hospitalization

The effect of probiotics on enteral milk tolerance and prevention of Necrotizing Enterocolitis in preterm infants hospitalization

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20141028019716N5
Enrollment
30
Registered
2022-08-05
Start date
2022-07-21
Completion date
Unknown
Last updated
2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

and prevention of Necrotizing Enterocolitis in preterm. Necrotizing enterocolitis in newborn, unspecified

Interventions

Intervention 1: intervention group: After the baby's feeding volume reaches 5 cc/kg/d, oral probiotics from Bio Fermentation Company at the rate of one drop per kilogram of body weight with normal sal

Sponsors

Bojnourd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
168 Months to 210 Days

Inclusion criteria

Inclusion criteria: Entry condition for pregnancy age below 30 weeks and birth weight less than 1500 grams

Exclusion criteria

Exclusion criteria: Babies with gastrointestinal obstruction, congenital heart disease, amphalocele, gastroschisis, grade 2 and 3 asphyxiaCommunity Verified icon Babies of addicted mothers(Because one of the problems of babies born to addicted mothers is digestive problems such as feeding intolerance and abdominal distention and diarrhea, which can overlap with the symptoms of necrotizing enterocolitis).Community Verified icon Failure to receive enteral nutrition in the first 48 hours of birth Death of a premature baby Congenital and chromosomal malformations in the digestive system of premature babies Active gastrointestinal bleeding in the first week after birth

Design outcomes

Primary

MeasureTime frame
Prevention of necrotizing enterocolitis. Timepoint: When a premature baby is hospitalized. Method of measurement: Definitive diagnosis of necrotizing enterocolitis by a neonatologist.

Secondary

MeasureTime frame
1. Duration of hospitalization. Timepoint: Weight of premature baby at admission and at discharge. Method of measurement: The weight of the premature baby is in grams at the time of hospitalization And the time is based on hours and minutes and Increase in head circumference based on centimeters.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Ghasem Bayani

Bojnourd University of Medical Sciences

bayani.ghasem@yahoo.com+98 58 4221 1008

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026