The effect of type of opioid drugs on hemodynamic parameters and pregnancy outcome in patients ?undergoing ovarian puncture ?

The clinical trial to compare the effect of fentanyl, remifentanil and alfentanil on hemodynamic ?parameters and pregnancy outcome in patients undergoing ovarian puncture ?

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201410258677N4

Enrollment

240

Registered

2015-01-21

Start date

2014-11-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

In vitro fertilization patients. Complications of attempted introduction of fertilized ovum following in vitro fertilization

Interventions

Intervention 1: In the first intervention group, induction of general anesthesia? will be performed? with administration of ?1.5 ????micrograms fentanyl, 40 ?milligrams lidokain and 2 ?milligrams prop

Treatment - Drugs

In the first intervention group, induction of general anesthesia? will be performed? with administration of ?1.5 ????micrograms fentanyl, 40 ?milligrams lidokain and 2 ?milligrams propofol

In the second intervention group, induction of general anesthesia? will be performed? with administration of 15 ???micrograms alfentanil?, ?40 ?milligrams lidokain and 2 ?milligrams propofol

In the third intervention group, induction of general anesthesia? will be performed? with administration of ?1.5 ???micrograms remifentanil?, 40 milligrams lidokain and 2 milligrams propofol

Eligibility

Sex/Gender

Female

Age

19 Years to 39 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age under ??40?? years; Fresh embryo transfer cycles. Exclusion criteria: Azoospermia; Follicle stimulating hormone level ?greater than ??10??; Polycystic ovarian syndrome; Endocrine ?disorders; Poor responders; Unexplained infertility; Cardiopulmonary disease; Chronic use of ?drugs?; Allergy; Difficult embryo transfers; Bloody catheter.?

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Blood pressure. Timepoint: Every three minutes. Method of measurement: Non-invasive.;Heart rate. Timepoint: Continuous monitoring. Method of measurement: Electrocardiogram - Pulse oximeter.;Pregnancy outcome. Timepoint: Two weeks and three months after embryo transfer. Method of measurement: Human chorionic gonadotropin test - Ultrasound.;Recovery time. Timepoint: Since the arrival of the patient to the recovery room until respond to voice commands. Method of measurement: Postanesthesia discharge scoring system.	—

Measure

Time frame

Blood pressure. Timepoint: Every three minutes. Method of measurement: Non-invasive.;Heart rate. Timepoint: Continuous monitoring. Method of measurement: Electrocardiogram - Pulse oximeter.;Pregnancy outcome. Timepoint: Two weeks and three months after embryo transfer. Method of measurement: Human chorionic gonadotropin test - Ultrasound.;Recovery time. Timepoint: Since the arrival of the patient to the recovery room until respond to voice commands. Method of measurement: Postanesthesia discharge scoring system.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Farnoush Farzi

Al-Zahra Hospital, Guilan University of Medical Sciences

farnoush_farzi@yahoo.com; farnoush_farzi@gums.ac.ir009813?33322021?

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Mar 2, 2026