Alpha-Lipoic acid supplementation on symptoms of dysmenorrhea

The effect of alpha-Lipoic Acid supplementation on symptoms of primary dysmenorrhea in students residing in the dormitory of Qazvin University of Medical Sciences : A randomized, single-blind, placebo-controlled clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20141025019669N8

Enrollment

Registered

2018-02-09

Start date

2018-02-04

Completion date

Unknown

Last updated

2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary dysmenorrhoea. Primary dysmenorrhea

Interventions

Intervention 1: Intervention group: Alfalipoic acid, 600 mg per daily. Intervention 2: Intervention group: Mefenamic acid, 250 mg per day. Intervention 3: Intervention group: Alfalipoic acid (600 mg)

Eligibility

Sex/Gender

Female

Age

18 Years to 25 Years

Inclusion criteria

Inclusion criteria: Having primary dysmenorrhea Having regular menstruation between 35-21 days Single Having a body mass index below 30

Exclusion criteria

Exclusion criteria: Having secondary dysmenorrhea (endometriosis, adenomyosis, leiomyoma, uterine anomaly, Endometrial Polyps, ovarian cyst) Intake of antioxidant supplement in the last six months

Design outcomes

Primary

Measure	Time frame
Duration of bleeding. Timepoint: Before the intervention and after the intervention. Method of measurement: According to a person's report by the questionnaire.;Pain duration. Timepoint: Before the intervention and after the intervention. Method of measurement: Duration of pain based on hours.;Intensity of pain. Timepoint: Before the intervention and after the intervention. Method of measurement: Pain intensity according to the questionnaire.	—

Measure

Time frame

Duration of bleeding. Timepoint: Before the intervention and after the intervention. Method of measurement: According to a person's report by the questionnaire.;Pain duration. Timepoint: Before the intervention and after the intervention. Method of measurement: Duration of pain based on hours.;Intensity of pain. Timepoint: Before the intervention and after the intervention. Method of measurement: Pain intensity according to the questionnaire.

—

Secondary

Measure	Time frame
Pain duration. Timepoint: Before the intervention and after the intervention. Method of measurement: Duration of pain based on hours.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHossein Khadem Haghighian

Qazvin University of Medical Sciences

khademnut@yahoo.com+98 28 3333 6001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026