Effect of probiotic and alpha-lipoic acid supplements on the maintenance of weigh in overweight individuals

The survey of oral supplementation effects with probiotic and alpha-lipoic acid, separately or in combination on the maintenance of weigh in overweight individuals under isocaloric weight loss diet

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20141025019669N10

Enrollment

Registered

2018-12-16

Start date

2018-11-30

Completion date

Unknown

Last updated

2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Simple obesity NOS. Obesity, unspecified

Interventions

Intervention 1: Intervention group: isocaloric diet based on the needs of the person with probiotic capsule, 500 mg per day for two months (Phase I of the study), probiotic capsule, 500 mg per day fou

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Overweight people according to WHO classification according to body mass index Age range from 18 to 65 years

Exclusion criteria

Exclusion criteria: Having an acute or chronic metabolic disorder

Design outcomes

Primary

Measure	Time frame
Weight. Timepoint: Before the intervention and after the intervention. Method of measurement: Weight of the participants with minimal dress and no shoes to the nearest 0.5 kg using a medical weight scale.;Blood pressure. Timepoint: Before the intervention and after the intervention. Method of measurement: By medical barometer.;Appetite. Timepoint: Before the intervention and after the intervention. Method of measurement: Scale Analog Visual questionnaire.;Body fat. Timepoint: Before the intervention and after the intervention. Method of measurement: Using of Deurenberg equation.;C reactive protein. Timepoint: Before the intervention and after the intervention. Method of measurement: Eliza.;Sleep quality. Timepoint: Before intervention and after intervention. Method of measurement: Petersburg’s sleep quality questionnaire.	—

Measure

Time frame

Weight. Timepoint: Before the intervention and after the intervention. Method of measurement: Weight of the participants with minimal dress and no shoes to the nearest 0.5 kg using a medical weight scale.;Blood pressure. Timepoint: Before the intervention and after the intervention. Method of measurement: By medical barometer.;Appetite. Timepoint: Before the intervention and after the intervention. Method of measurement: Scale Analog Visual questionnaire.;Body fat. Timepoint: Before the intervention and after the intervention. Method of measurement: Using of Deurenberg equation.;C reactive protein. Timepoint: Before the intervention and after the intervention. Method of measurement: Eliza.;Sleep quality. Timepoint: Before intervention and after intervention. Method of measurement: Petersburg’s sleep quality questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactHossein Khadem Haghighian

Qazvin University of Medical Sciences

khademnut@yahoo.com+98 28 3333 6001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 24, 2026