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Study the effect of Ultrasound-Guided Sacroiliac joint single dose platelet-rich plasma injection in patients with sacroiliac joint pain. A, single-arm, before and after, open-label clinical trial

Study the effect of Ultrasound-Guided Sacroiliac joint single dose platelet-rich plasma injection in patients with sacroiliac joint pain. A, single-arm, before and after, open-label clinical trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20141023019640N4
Enrollment
26
Registered
2024-09-01
Start date
2024-09-18
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sacroiliac joint pain. Chronic pain, not elsewhere classified

Interventions

Intervention group: PRP injection (Royagen kits, made by Aria Mobna Diagnos Company) is performed as a single dose with a volume of 10 cc..

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients aged 20-60 years with sacroiliac joint pain and an NRS (Numeric Rating Scale) score greater than 5 during the last three months, based on clinical examinations and positive results of three sacroiliac joint provocative tests (Faber, Gaenslen, iliac compression, Fortin Finger, Yeoman, thigh thrust, iliac distraction), will be included in the study.

Exclusion criteria

Exclusion criteria: Thrombocytopenia (platelets less than 150,000 per microliter), local infection at the injection site, use of non-steroidal anti-inflammatory drugs within 48 hours before injection, use of systemic corticosteroids within a month before injection, malignancy, pregnancy, rheumatological diseases, Uncontrolled hormonal disorders, systemic inflammatory diseases, neurological or psychological disorders, age less than 20 years or more than 60 years, patients with midline pain above the level of the fifth lumbar vertebra.

Design outcomes

Primary

MeasureTime frame
Pain Intensity. Timepoint: The patient's pain intensity is measured before the intervention and at one and three months after the intervention (PRP injection into the sacroiliac joint). Method of measurement: Numeric Rating Scale (NRS).

Secondary

MeasureTime frame
Functionality. Timepoint: The patient's functional improvement is measured before the intervention and at one and three months after the intervention (PRP injection into the sacroiliac joint). Method of measurement: Oswestry Disability Index (ODI).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Hossein Majedi Ardakani

Tehran University of Medical Sciences

hmajedi@tums.ac.ir+98 21 6658 1627

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026