Effect of transurethral plasma rich platelet combined with autologous fat injection versus autologous fat injection on abdominal leak point pressure in patient with stress urinary incontinence

Effect of transurethral plasma rich platelet combined with autologous fat injection versus autologous fat injection on abdominal leak point pressure in patient with stress urinary incontinence: a double blinded randomized clinical trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201410219014N44

Enrollment

Registered

2014-10-27

Start date

2012-09-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stress urinary incontinence. Stress incontinence

Interventions

Intervention 1: Transurethral injection of 25 ml plasma rich platelet combined with 25 ml autologous fat single dose. Intervention 2: Transurethral injection of 25 ml autologous fat single dose.

Treatment - Drugs

Transurethral injection of 25 ml plasma rich platelet combined with 25 ml autologous fat single dose.

Transurethral injection of 25 ml autologous fat single dose.

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Inclusion criteria: (a) patients with stress urinary incontinence; (b) abdominal leak point pressure less than 100 cm of water. Exclusion criteria: (a) hyperactivity of the detrusor muscle; (b) contraindication of anesthesia; (c) presence of anatomical disorder in bladder; (d) platelet disorder.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Evaluation of improvement of urinary incontinence. Timepoint: before intervention and every 3 months after intervention for 18 months. Method of measurement: by history taking.	—

Secondary

Measure	Time frame
Evaluation of urinary retention. Timepoint: one week after intervention. Method of measurement: by history taking.;Thromboembolism. Timepoint: 48 hours after intervention. Method of measurement: by physical examination.;Urinary infection. Timepoint: one week after intervention. Method of measurement: by history taking.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Masood Jafari

Shahid Beheshti Hospital

m.jafari2442 @gmail.com+98 81 3838 0717

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026