The Effects of Vitamin E And Folic Acid on The improvement of acute hemolysis Due of deficient G6PD on the children refer to the 17th Shahrivar hospital in Rasht, 2014.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014102019541N1

Enrollment

120

Registered

2014-11-04

Start date

2014-05-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glucose 6 Phosphate Dehydrogenase Deficiency. Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency

Interventions

Intervention 1: first group(100 mg vitamin E for children aged 1-2 years, 200 mg for children aged 2-3 years, 300 mg for children aged 3-4 years and 400 mg for children aged more than 4 years) 2 weeks

Treatment - Drugs

first group(100 mg vitamin E for children aged 1-2 years, 200 mg for children aged 2-3 years, 300 mg for children aged 3-4 years and 400 mg for children aged more than 4 years) 2 weeks, oral

Third group 100 mg vitamin E for children aged 1-2 years, 200 mg for children aged 2-3 years, 300 mg for children aged 3-4 years and 400 mg for children aged more than 4 years and 2mg folic acid dail

Second group 2mg folic acid daily for children aged 1-2 years and 5 mg folic acid daily for children aged more than 2 years. 2 Weeks oral

control group: no treatment will be adminstered

Eligibility

Sex/Gender

All

Age

1 Years to 14 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria : age: 1-14 yeaers; G6PD deficient children; acutephase hemolysis; no use of vitamine E or folic acid during past 1 months. exclusion criteria : no referal for followup labaratory examinations; death before the end of the study; hemolysis consequent to other causes exept G6PD deiciency

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
The level of Hemoglobine. Timepoint: Before Intervention and 2 Weeks after the initiation of intervention. Method of measurement: Based on gram per deciliter with the complete bloodcells count examination.	—

Secondary

Measure	Time frame
Assessing the level of reticoluocyte. Timepoint: before interventions and 2 weeks after the initiation of intervention. Method of measurement: the percentage of reticoluocytes derived from complete bloodcells count.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Adel Baghersalimi

Guilan University Of Medical Sciences

baghersalimi498@gums.ac.ir+98 13 3332 6101

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026