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Using different modes of ventilation after coronary artery bypass graft surgery

Determining and comparing the effect of Adaptive Support Ventilation and Synchronized Intermittent Mandatory Ventilation on respiratory support outcomes after Coronary Artery Bypass Graft surgery, Isfahan University of Medical sciences, Chamran hospital, 2014

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014101919584N1
Enrollment
64
Registered
2014-12-30
Start date
2014-04-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atherosclerotic heart disease. Atherosclerotic heart disease

Interventions

Intervention 1: Description: In this study, patients after undergoing Coronary Artery Bypass Graft surgery (CABG) and transferring to the intensive care unit (ICU) while intubated, with approval of an
Treatment - Other
Treatment - Drugs
Description: In this study, patients after undergoing Coronary Artery Bypass Graft surgery (CABG) and transferring to the intensive care unit (ICU) while intubated, with approval of an anesthesiologis
Control group: Using Synchronized Intermittent Mandatory Ventilation mode for respiratory ventilation after coronary artery bypass graft surgery in intensive care unit

Sponsors

Vice chancellor for research, Isfahan university of medical sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 65 Years

Inclusion criteria

Inclusion criteria: Main inclusion criteria: Using one of the ventilation modes (Adaptive support ventilation (ASV) or synchronized intermittent mandatory ventilation (SIMV)) on Raphael ventilator was allowed by anesthesiologist; The range of age was between 25 and 65 years; Patients did not have a history of lung diseases (Asthma, ...) or lung and heart surgeries; Patients did not have renal failure (serum creatinine more than 2), liver disease, and history of seizure and CVA; left ventricular ejection fraction was more than 30 percent; In the time of ICU entrance patients were haemodynamically stable ( respiratory rate less than 35 per minute, heart rate less than 150 per minute, mean atrial pressure less than 70 mmHg) and intra aortic balloon pump was not used. Main exclusion criteria: occurring unstable haemodynamic status during research (respiratory rate more than 35 per minute, heart rate more than 150 per minute, mean atrial pressure more than 70 mmHg); life threatening arrhythmia durin research like ventricular tachycardia; need to excess dosages of inotropes and vasoconstrictors during research (Dopamin more than 20 milligram per hour, norepinephrin more than 0.5 milligram per hour, dobotamin more than 25 milligram per hour, and epinephrin with any doses); Unusual bleeding after operation (chest tube drainage more than 500 ml per hour, more than 350 ml per hour for 2 hours, or more than 1000 ml at all) ; Need to anesthesia and operation again.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Intubation duration. Timepoint: When the intervention starts. Method of measurement: Hour and minutes.;Length of hospital stay. Timepoint: When the patient is being discharged. Method of measurement: Hour and minutes.

Secondary

MeasureTime frame
Nothing. Timepoint: nothing. Method of measurement: nothing.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHadi Zarei

Isfahan university of medical sciences, faculty of nursing and midwifery

hadi.zarei767@gmail.com+98 31 3792 2901

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026