Condition 1: Knee Osteoarthritis. Condition 2: Knee Osteoarthritis. Other Arthritis Arthropathy in other diseases
Conditions
Interventions
Intervention 1: Intervention group : 10 cc dextrose 50% plus 4 unit uotropin and 10 cc ozone 25 microgram is injected into the knee. Intervention 2: Control group : 10 cc dextrose 50% and 4
Treatment - Other
Treatment - Drugs
Intervention group : 10 cc dextrose 50% plus 4 unit uotropin and 10 cc ozone 25 microgram is injected into the knee.
Control group : 10 cc dextrose 50% and 4 unit uotropin is injected into the knee.
Sponsors
Vice chancellor for research, Iran University of Medical Science
Eligibility
Sex/Gender
All
Age
25 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion citeria: 1, 25-70 years old patients with primary Osteoarthritis attended in clinic or pain section were selected for the experiment. 2, considering general criteria the patient were belonged to ASA 1-2. 3, Before the onset of experiment the volunteer patients were asked to sign an agreement supplied by the Moral Committee of the Iran University of Medical Science. 4, Accurate visit of the recognition of the primary Osteoarthritis symptoms was accomplished based on the American Rheumatology Association standards. Exclusion criteria: 1, Alchol and opium addiction. 2, Hemophilia. 3, Rheumatoid Arthritis.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: First, third and fifth weeks after the first injection and four months after the last injection. Method of measurement: VAS. | — |
Secondary
| Measure | Time frame |
|---|---|
| Range of motion and knee stiffness. Timepoint: First, third and fifth weeks after the last injection and four months after the last injection. Method of measurement: WOMAC score. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Farnad Imani
Rasoul Akram Hospital
Outcome results
None listed