The effect of orange peel essential oil on postpartum anxiety and depression

The effect of orange peel essential oil on postpartum anxiety and depression : a randomized controlled trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014101210324N21

Enrollment

Registered

2014-12-30

Start date

2014-11-19

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anxiety and depression. Mixed anxiety and depressive disorder

Interventions

Intervention 1: The intervention group will receive orange peel essential oil,10 drops oral 3 times a day for eight weeks. Intervention 2: The control group will receive placebo including Propylene gl

Treatment - Drugs

The intervention group will receive orange peel essential oil,10 drops oral 3 times a day for eight weeks.

The control group will receive placebo including Propylene glycol and water 10 drops 3 times daily for 8 weeks.

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 18 years and older women; Residence in Tabriz city; Having literacy; Women delivered at 48 hours ago (nulliparous or multiparous); Vaginal or cesarean delivery; Having a low-risk pregnancy; Willingness to participate in the study; Having care record in nearest health center; Having the home telephone or mobile number; Getting score lower than 12 according to Edinburg scale. Exclusion criteria: Having depression disorder before delivery according to self-expression; Neonatal death or neonate bedridden in Neonatal Intensive Care Unit (NICU); Stillbirth; Mothers who bedridden for postpartum complications; Having a bad event at three month ago such as death or hospitalization of a family member; Having chronic disease such as liver or kidney disease; Having repeated abortion

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Depression. Timepoint: Before intervention and eight weeks after intervention. Method of measurement: Edinburg questionnaire.;Anxiety. Timepoint: Before intervention and eight weeks after intervention. Method of measurement: Spilberger questionnaire.	—

Secondary

Measure	Time frame
Patients satisfaction level from treatment. Timepoint: During eight weeks of intervention. Method of measurement: Questionnaire.;Frequency of side events of drug. Timepoint: During eight weeks of intervention. Method of measurement: Side event questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMina Galeshi

Tabriz University of Medical Sciences

galeshi_m@yahoo.com+98 41 3479 6770

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026