The effect of urodeoxy cholic acid on prevention of gall stone formation after bariatric surgery

Urodeoxy cholic acid prescription for gallstone prevention after gastric bypass surgery , comparison of prescription till 50% wight loss with 6 month prescription

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201410118588N20

Enrollment

192

Registered

2015-12-02

Start date

2015-09-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gallstone. Cholelithiasis

Interventions

Intervention 1: Intervention group receives 600 mg urodeoxycholic acid daily, until 50% excessive weight loss after surgery. Intervention 2: Intervention group receives 600 mg urodeoxycholic acid dai

Prevention

Intervention group receives 600 mg urodeoxycholic acid daily, until 50% excessive weight loss after surgery.

Intervention group receives 600 mg urodeoxycholic acid daily, 6 months after surgery.

Eligibility

Sex/Gender

All

Age

15 Years to 68 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age > 18; BMI >40 or BMI<35 with an obesity comorbidity; Exclusion criteria: past history of cholecystectomy; gallstone in sonography before surgery; using drugs with imteracting urodeoxycholic acid; cirrhosis; hemolytic disease; intolerance of urodeoxy cholic acid; no correct use of urodeoxy cholic acid

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Gallstone formation. Timepoint: 6 monthes after surgery, at 50% weight loss after surgery. Method of measurement: sonography.	—

Secondary

Measure	Time frame
Weight. Timepoint: 6 monthes after surgery, at 50% weight loss after surgery. Method of measurement: Balance.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Nazari

Minimally Invasive Surgery Research Center

zanazari87@gmail.com00219866555447

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026