Effect of a natural cream on hemorrhoids in comparison with the conventional ointment

Effect of a natural cream on hemorrhoids in comparison with conventional anti-hemorrhoid ointment: A double-blind controlled trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20141011019489N3

Enrollment

Registered

2020-04-20

Start date

2018-09-22

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Hemorrhoid. Condition 2: Hemorrhoid. First degree hemorrhoids Second degree hemorrhoids

Interventions

Intervention 1: Intervention group: Herbal cream containing the extract of oleaster, wild leek and camomile, and the essence of common myrtle. Route of administration and dose: Locally one gram on the

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age: 18 and more Hemorrhoid Grade 1,2

Exclusion criteria

Exclusion criteria: Any types of malignancy Hypertension Hepatic or renal failure Diabetes mellitus

Design outcomes

Primary

Measure	Time frame
Manifestations of hemorrhoid. Timepoint: The onset of the intervention, 2 weeks later, 6 weeks later. Method of measurement: A checklist for hemorrhoid manifestations including 1- Anal pain (VAS zero to 10) 2- Difficulty in defecation (VAS zero to 10) 3- Bleeding severity (4-point Likert) 4- Anal pruritus (4-point Likert) 5- Anal burning (4-point Likert) 6- Subjective general improvement (percent).	—

Measure

Time frame

Manifestations of hemorrhoid. Timepoint: The onset of the intervention, 2 weeks later, 6 weeks later. Method of measurement: A checklist for hemorrhoid manifestations including 1- Anal pain (VAS zero to 10) 2- Difficulty in defecation (VAS zero to 10) 3- Bleeding severity (4-point Likert) 4- Anal pruritus (4-point Likert) 5- Anal burning (4-point Likert) 6- Subjective general improvement (percent).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Ebrahim Zohalinezhad

Shiraz University of Medical Sciences

zohalinm@sums.ac.ir+98 71 3208 4241

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026