missed abortion. Early fetal death with retention of dead fetus
Conditions
Interventions
Intervention 1: The intervention in oral group will be done by administering 600 µg of misoprostol every 6 hours (up to 4 doses) orally in pregnant women with missed abortion. Intervention 2: The int
Treatment - Drugs
The intervention in oral group will be done by administering 600 µg of misoprostol every 6 hours (up to 4 doses) orally in pregnant women with missed abortion.
The intervention in vaginal group will be done by administering 600 µg of misoprostol every 6 hours (up to 4 doses) vaginally in pregnant women with missed abortion.
The intervention in sublingual group will be done by administering 600 µg of misoprostol every 6 hours (up to 4 doses) vaginally in pregnant women with missed abortion.
Sponsors
Sabzear University of Medical Science
Eligibility
Sex/Gender
Female
Age
16 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion criteria are gestational age less than 14 weeks; confirmation of the need for pregnancy termination by ultrasound. Exclusion criteria are the vaginal bleeding; emergency need for surgery to pregnancy termination; anemia; Coagulation disorders or taking anticoagulant;, history of diseases (liver, kidney and heart); history of allergy to prostaglandin; smoking; inflammatory diseases and hemoglobin less than 9 g/dl.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of compelete abortion. Timepoint: Compelete abortion during 7 days. Method of measurement: Complete evacuation of the uterus by ultrasound. | — |
Secondary
| Measure | Time frame |
|---|---|
| The intensity and duration of bleeding. Timepoint: Up to 7 days. Method of measurement: Higham chart. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahbobe Mohebbi
Member of research committee in Sabzevar University of Medical Sciences
Outcome results
None listed