Condition 1: Opium Addiction. Condition 2: Orthopaedic Surgery. Mental and behavioural disorders due to use of opioids Fracture of Bone following Insertion of Orthopaedic Implant, Joint Prosthesis, or Bone Plate
Conditions
Interventions
Intervention 1: Intervention Group 1: 0.15 mg/kg Morphine Given to the Patients an Hour before the Completion of the Surgery. Intervention 2: Intervention Group 1: 0.15 mg/kg Methadone Given to the P
Treatment - Drugs
Intervention Group 1: 0.15 mg/kg Morphine Given to the Patients an Hour before the Completion of the Surgery
Intervention Group 1: 0.15 mg/kg Methadone Given to the Patients an Hour before the Completion of the Surgery
Sponsors
Vice Chancellor for Research, Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: opium -addicted patients, aged of 18-70 years undergoing major orthopedic surgeries. Exclusion criteria: patients with a history of myocardial infarction, heart failure, patients with ASA class above III, patients using anti-depressant drugs, a history of allergy to the drugs and patients who need ICU after surgery.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of the postoperative pain in major orthopedic surgery in patients addicted to opium. Timepoint: Immediately after surgery and one hour, three hours, six hours and 24 hours after surgery. Method of measurement: NRS. | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient's satisfaction. Timepoint: Immediately after surgery and one hour, three hours, six hours and 24 hours after surgery. Method of measurement: Four Point Categorical Scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAfsoon Aleepour
Shiraz University of Medical Sciences
Outcome results
None listed