anxiety and depression. Mixed anxiety and depressive disorder
Conditions
Interventions
Intervention 1: The first intervention group will receive Zinc sulfate tablet 27 mg oral, once a day for eight weeks. Intervention 2: The second intervention group will receive Magnesium sulfate table
Treatment - Drugs
The first intervention group will receive Zinc sulfate tablet 27 mg oral, once a day for eight weeks
The second intervention group will receive Magnesium sulfate tablet 320 mg oral, once a day for eight weeks
The control group will receive placebo tablet like Zinc sulfate and Magnesium sulfate, once a day for eight weeks
Sponsors
Vice chancellor for research, Tabriz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 18 years and older women; Residence in Tabriz city; Having literacy; Women delivered at 48 hours ago (nulliparous or multiparous); Vaginal or cesarean delivery; Having a low-risk pregnancy; Willingness to participate in the study; Having care record in nearest health center; Having the home telephone or mobile number; Getting score lower than 12 according to Edinburg scale. Exclusion criteria: Having depression disorder before delivery according to self-expression; Neonatal death or neonate bedridden in Neonatal Intensive Care Unit (NICU); Stillbirth; Mothers bedridden for postpartum complications; Having a bad event at three month ago such as death or hospitalization of a family member; Having a chronic disease such as liver or kidney disease; Having repeated abortion.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anxiety. Timepoint: Before intervention and eight weeks after intervantion. Method of measurement: Spilberger questionnaire.;Depression. Timepoint: Before intervention and eight weeks after intervantion. Method of measurement: Edinburg questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Relationship between zinc and magnesium serum level with anxiety score. Timepoint: Before intervantion. Method of measurement: Spectophotometry and Randox kit.;Relationship between zinc and magnesium serum level with depression score. Timepoint: Before intervantion. Method of measurement: Spectophotometry and Parsazmoon kit.;Satisfaction of patients receiving treatment. Timepoint: during eight weeks of intervention. Method of measurement: Satisfaction of patients of treatment questionnaire.;Frequency of side events of drug. Timepoint: During eight weeks of intervention. Method of measurement: Side event questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFateme Edalati Fard
Nursing & Midwifery Faculty,Tabriz University of Medical Sciences
Outcome results
None listed