Breast Cancer. Intraductal carcinoma in situ of unspecified breast
Conditions
Interventions
Intervention 1: Intervention group:Patients are given 0.2 mg of clonidine tablets in the morning. Intervention 2: Control group:Control group: Patients are given one tablet in the morning as a placebo
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
15 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients Candidate for Breast Cancer Surgery Ages 15 to 70 years ASA Class I-II General Anesthesia
Exclusion criteria
Exclusion criteria: A history of postoperative nausea and vomiting Patients who have received antiemetic drugs such as ondansetron or dexamethasone 24 hours before surgery History of motion sickness Allergy to Propofol and Clonidine Concomitant use of beta-blocker medication that may affect a patient's heart rate Systolic blood pressure less than 100 History of using Steroid History of myocardial infarction History of tricyclic antidepressant use History of kidney dysfunction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Post-operative Nausea and Vomiting. Timepoint: Postoperative nausea and vomiting in recovery is recorded at 0-15-30 and 45 minutes. After transferring the patient to the surgical ward, the incidence of postoperative nausea and vomiting is evaluated at 6 and 24 hours. Method of measurement: Likert. | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic changes. Timepoint: Blood pressure and heart rate are recorded in the surgical ward in the operating room before induction after induction and in recovery at 0-15-30 and 45 minutes.After transferring the patient to the surgical ward, the patient's blood pressure is checked at 24,2,4,6,12 hours. Method of measurement: Monitoring. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShabnam Heidarynezhad
Shiraz University of Medical Sciences
Outcome results
None listed