Cesarean Section. Onset (spontaneous) of labor after 37 completed weeks of gestation but before 39 completed weeks gestation, with delivery by (planned) cesarean section
Conditions
Interventions
Intervention 1: Intervention group: Patients will receive acetaminophen caffeine tablets (acetaminophen 500 mg + caffeine 65 mg) for 2 hours before spinal anesthesia and again every 6 hours up to 24 h
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Pregnant women candidates for elective cesarean section ASA I-II Minimum NPO time of 8 hours Single pregnancy
Exclusion criteria
Exclusion criteria: Spinal anesthesia contraindications Diabetes Kidney failure Coagulopathy Liver disease Heart disease History of seizures, Neurological disease, Migraine and pressure headaches, History of opium addiction, Failure of spinal anesthesia, or repeated attempts to perform spinal anesthesia, Systolic pressure greater than 150 and less than 100, Preeclampsia, Fetal anomaly , Intrauterine growth restriction Weight above 100, height less than 150 and more than 180 cm Hemoglobin less than 8, Cesarean section more than 3 times and Allergy to acetaminophen caffeine.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Post-Dural Puncture Headache. Timepoint: Two hours after spinal anesthesia and at 6,12,18,24 after receiving the first dose of Acetaminophen ,Caffeine and then 48 and 72 hour post-operative. Method of measurement: Visual Analog Score (VAS).;Post-Operative Nausea and Vomiting. Timepoint: Two hours after spinal anesthesia and at 6,12,18,24 after receiving the first dose of Acetaminophen ,Caffeine and then 48 and 72 hour post-operative. Method of measurement: Likert. | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure. Timepoint: During surgery. Method of measurement: Monitoring. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSona Shahmohammadi
Shiraz University of Medical Sciences
Outcome results
None listed