Acute cholecystitis. Calculus of gallbladder with acute cholecystitis
Conditions
Interventions
Intervention 1: Intervention group: Immediately after endotracheal intubation, lidocaine 2% solution (1.5 mg / kg) will be administered slowly. Then lidocaine 2% infusion at 2 mg / kg dose will start
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: ASA I-II Age 18 to 75 years Patients Candidate for Laparoscopic Cholecystectomy
Exclusion criteria
Exclusion criteria: Non-cooperation patients after surgery Severe physical and mental disorders Severe bradycardia (heart rate less than 40 times per minute) Severe bleeding leading to laparotomy A history of allergies to topical anesthetics and lidocaine and opioids Chronic use of opioids and nonsteroidal anti-inflammatory drug and alcohol Pregnancy History of heart, liver and kidney failure The heart rate is less than 50 minutes per minute and any block on the ECG
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of pain in recovery. Timepoint: On arrival to recovery and every 15 minutes to 60 minutes in recovery. Method of measurement: NRS.;Severity of pain in the ward. Timepoint: Every one hour up to 6 hours, and then 12 and 24 hours. Method of measurement: NRS. | — |
Secondary
| Measure | Time frame |
|---|---|
| Sedation Score. Timepoint: At the arrival to the recovery room. Method of measurement: four-point categorical scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmir Javadi
Shiraz University of Medical Sciences
Outcome results
None listed