Comparison of albumin-normal saline and albumin-gelatin injection on early outcome after liver transplant surgery

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20141009019470N88

Enrollment

100

Registered

2019-09-17

Start date

2019-09-21

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver transplant. Liver transplant status

Interventions

Intervention 1: Intervention group: In group 1, 10 grams of albumin in 1000 cc normal saline is infused from the beginning to the end of the procedure. Intervention 2: Intervention group: In group two

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: The final stage of liver disease Age over 18 years Patients candidate for liver transplantation from brain death donors

Exclusion criteria

Exclusion criteria: Liver recipients from live donors Patients undergoing redo transplantation History of upper abdominal surgery A history of allergies to colloids History of kidney dysfunction confirmed by laboratory and ultrasound tests

Design outcomes

Primary

Measure	Time frame
Glomerular filtration rate. Timepoint: On the first day, second day, third day, fifth day and the last day of hospitalization. Method of measurement: Cochcroft and Gault formula.;Serum creatinine level. Timepoint: On the first day, second day, third day, fifth day and the last day of hospitalization. Method of measurement: Venous blood sample.;Blood Urea Nitrogen. Timepoint: On the first day, second day, third day, fifth day and the last day of hospitalization. Method of measurement: Venous blood sample.;Liver Function Tests: (AST, ALT, ALKP, INR, Bilirubin), Albumin. Timepoint: On the first day, second day, third day, fifth day and the last day of hospitalization. Method of measurement: Venous blood sample.	—

Measure

Time frame

Glomerular filtration rate. Timepoint: On the first day, second day, third day, fifth day and the last day of hospitalization. Method of measurement: Cochcroft and Gault formula.;Serum creatinine level. Timepoint: On the first day, second day, third day, fifth day and the last day of hospitalization. Method of measurement: Venous blood sample.;Blood Urea Nitrogen. Timepoint: On the first day, second day, third day, fifth day and the last day of hospitalization. Method of measurement: Venous blood sample.;Liver Function Tests: (AST, ALT, ALKP, INR, Bilirubin), Albumin. Timepoint: On the first day, second day, third day, fifth day and the last day of hospitalization. Method of measurement: Venous blood sample.

—

Secondary

Measure	Time frame
ICU stay. Timepoint: At arrival time until the discharge from intensive care unit. Method of measurement: Observation.;Time interval between completion of operation and extubation. Timepoint: Between completion of operation to extubation. Method of measurement: Observation.;Hospital Stay. Timepoint: Hospital discharge time. Method of measurement: Observation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSamaneh Ghazanfar Tehran

Shiraz University of Medical Sciences

Tehranisamaneh88rasht@gmail.com+98 71 3647 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026