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Comparison of prevalence of nausea and vomiting after laparascopic cholecystectomy in case of pretreatment with Haloperidol and Ondansetron

Comparison of prevalence of nausea and vomiting after laparascopic cholecystectomy in case of pretreatment with Haloperidol and Ondansetron

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20141009019470N85
Enrollment
60
Registered
2019-08-07
Start date
2019-08-07
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopy Cholecystectomy. Calculus of gallbladder with other cholecystitis

Interventions

Intervention 1: Intervention group: patients in the group one received 0.05 mg/kg IV. Haloperidol during 5 min after induction of anesthesia. Intervention 2: Intervention group: patients in the group

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age 18--60 years old Patients undergoing laparoscopy cholecystectomy under general anesthesia Cholelithiasis Chronic cholecystitis Cholecystic polyp ASA I-II

Exclusion criteria

Exclusion criteria: Underlying medical condition that is currently not under control History of allergy to drugs or use of alcohol; Parkinson History of glaucoma Bone marrow depression Severe liver disease Obstructive bowel disease History of prostate disease History of cardiac arrhythmia History of respiratory failure or respiratory distress Taking antidepressants History of allergy to haloperidol or ondansetron Pregnancy Breast feeding patients Digestive diseases, kidney and hematology History of dizziness or motion Use an anti-nausea and vomiting agent within 24 hours before the surgery Anxiety disorders,Restlessness, loss in time and place Confusion, tremor, chills, seizure, tinnitus History of Bradycardia Reduced cardiac function Low blood pressure Surgery takes more than an hour. Opium addiction

Design outcomes

Primary

MeasureTime frame
Post-operative Nausea and Vomiting. Timepoint: Every 15 min at the recovery room and every 1 hour at the ward. Method of measurement: Bellville Scoring.

Secondary

MeasureTime frame
Length of stay in the recovery room and the discharge time from recovery room. Timepoint: Every 15 min at the recovery room. Method of measurement: Aldrete Score.;Patients’ Satisfaction. Timepoint: At the end of the trial. Method of measurement: Likert scoring.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElisa Ramedani

Shiraz University of Medical Sciences

ramedani1363@yahoo.com+98 71 3647 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026