Coronary Artery Bypass Grafting surgery and cardiopulmonary bypass. Atherosclerotic heart disease of native coronary artery
Conditions
Interventions
Intervention 1: Intervention group: Patients in the dexmedmotidine group received doses of dexmedmotidine infusion at a dose of 0.5 micrograms / kg / h after induction of anesthesia until transmitted
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
No minimum to 70 Years
Inclusion criteria
Inclusion criteria: Age less than 70 years Patients undergoing coronary artery bypass graft surgery
Exclusion criteria
Exclusion criteria: Emergency Surgery Redo Surgery Performing a coronary artery bypass graft surgery with other cardiac surgery Preoperative renal problems and serum creatinine levels higher than 1.4 Ejection fraction less than 40% Known liver problems or high levels of liver enzymes Using balloon pump inside aorta.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum creatinine level. Timepoint: Before surgery, on the first, second and third days after surgery in ICU. Method of measurement: Blood sample.;Blood Urea Nitrogen. Timepoint: Before surgery, on the first, second and third days after surgery in ICU. Method of measurement: Blood sample.;Glomerular filtration rate. Timepoint: Before surgery, on the first, second and third days after surgery in ICU. Method of measurement: Cockcroft-Gault Equation Formula. | — |
Secondary
| Measure | Time frame |
|---|---|
| Inotropic Consumption in ICU. Timepoint: Before surgery, on the first, second and third days after surgery in ICU. Method of measurement: Observation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHamid Reza Lotfi
Shiraz University of Medical Sciences
Outcome results
None listed