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Comparing two different intravenous doses of granisetron in prevention of spinal Anesthesia induced shivering in cesarean section.

Comparing two different intravenous doses of granisetron in prevention of spinal Anesthesia induced shivering in cesarean section.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20141009019470N81
Enrollment
260
Registered
2019-06-18
Start date
2019-07-06
Completion date
Unknown
Last updated
2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean delivery. Newborn (suspected to be) affected by Cesarean delivery

Interventions

Intervention 1: Intervention group: First intervention group: Patients receive 3 mg ofintravenous Granisetron during 5 minutes prior to spinal anesthesia. Intervention 2: Intervention group: Second i

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: ASA I-II Aged 18 to 40 Elective cesarean section

Exclusion criteria

Exclusion criteria: Addicted to drug History of neuromuscular diseases Cardiac failure grade 3 and 4 Contraindication of the spinal anesthesia History of hypertension or cardiovascular disease Temperature is less than 36.5 ° C or above 38 ° before surgery Hypothyroidism or Hyperthyroidism The need for blood transfusion during surgery and medications that cause changes in body temperature or nausea and vomiting. The history of shivering from the operation Failure of the spinal anesthesia leading to general anesthesia History of sensitivity to Granisetron or ondonestrone.

Design outcomes

Primary

MeasureTime frame
Shivering. Timepoint: Peri-operatively and in the recovery room every 10 min. Method of measurement: Tsai and Chu Table.;Nausea and Vomiting. Timepoint: Peri-operatively and in the recovery room every 10 min and in the ward every 2,4,6 and 12 hour postoperatively. Method of measurement: Visual analog score.

Secondary

MeasureTime frame
Apgar score. Timepoint: At 1,5 min after birth. Method of measurement: Apgar score.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehdi Hamedi

Shiraz University of Medical Sciences

dr.m.hamed123@gmail.com+98 71 3647 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026