The effect of aminophyllin on renal function after liver transplant surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20141009019470N79

Enrollment

100

Registered

2019-04-06

Start date

2019-05-05

Completion date

Unknown

Last updated

2019-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

kidney transplant. Complications of kidney transplant

Interventions

Intervention 1: Intervention group: Patients in the intervention group receive 5 mg / kg of aminophylline as bolus after induction of anesthesia and then receive aminophylline infusion at a dose of 0.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients who are undergoing liver transplant surgery.

Exclusion criteria

Exclusion criteria: History of cardiac arrhythmia Tachycardia Renal injury Obstructive uropathy Congenital anomalies of the kidney Creatinine above 1.5 Sodium level less than 135 Patients who use of donated cadaver liver

Design outcomes

Primary

Measure	Time frame
Glomerular filtration rate. Timepoint: Before the operation and daily until 5 days post-operatively. Method of measurement: Cochcroft and Gault formula.;Serum creatinine level. Timepoint: Before the operation and daily until 5 days post-operatively. Method of measurement: Venous blood sample.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Hossein Eghbal

Shiraz University of Medical Sciences

hoseineghbal@yahoo.com+98 71 3647 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026