Preoperative hemodynamic Changes after Continuing or discontinuing Regular Angiotensin Converting Enzyme Inhibitors before Cataract Surgery a Comparative Study

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20141009019470N78

Enrollment

200

Registered

2019-04-06

Start date

2019-05-05

Completion date

Unknown

Last updated

2019-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cataract. Age-related cataract

Interventions

Intervention 1: Intervention group: Chronic ACEI users who do not stop their medication until the surgery. Intervention 2: Control group: Chronic ACEI users who discontinue their medication 24 to 12

Eligibility

Sex/Gender

All

Age

40 Years to 70 Years

Inclusion criteria

Inclusion criteria: ASA II Patients who are undergoing Cataract Surgery Ejection fraction higher than 40 % Patients with chronic use of ACEI (Angiotensin Converting Enzyme Inhibitors) or ARB(Angiotensin Receptor Blocker) .

Exclusion criteria

Exclusion criteria: Duration of operation more than 90 min Electrolyte imbalance Liver or Kidney dysfunction

Design outcomes

Primary

Measure	Time frame
Blood pressure. Timepoint: The patient's initial blood pressure will be recorded after entering the operating room and then every 5 minutes after induction of anesthesia and during the operation. In the recovery room, blood pressure will be checked every 10 minutes for 1 hour. Method of measurement: Pressure cuff.;Heart Rate. Timepoint: The patient's initial heart rate will be recorded after entering the operating room and then every 5 minutes after induction of anesthesia and during the operation. In the recovery room, heart rate will be checked every 10 minutes for 1 hour. Method of measurement: Monitoring.	—

Measure

Time frame

Blood pressure. Timepoint: The patient's initial blood pressure will be recorded after entering the operating room and then every 5 minutes after induction of anesthesia and during the operation. In the recovery room, blood pressure will be checked every 10 minutes for 1 hour. Method of measurement: Pressure cuff.;Heart Rate. Timepoint: The patient's initial heart rate will be recorded after entering the operating room and then every 5 minutes after induction of anesthesia and during the operation. In the recovery room, heart rate will be checked every 10 minutes for 1 hour. Method of measurement: Monitoring.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Ghadimi

Shiraz University of Medical Sciences

maryam_ghadimi2005@yahoo.com+98 36474270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 10, 2026