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Comparison effects of intravenous and local lidocain and remifentanil on hemodynamic changes during tracheal intubatin in hypertensive patients

Comparison effects of intravenous and local lidocain and remifentanil on hemodynamic changes during tracheal intubatin in hypertensive patients

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20141009019470N116
Enrollment
90
Registered
2021-04-13
Start date
2021-04-18
Completion date
Unknown
Last updated
2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypertension. Essential (primary) hypertension

Interventions

Intervention 1: Intervention group: Two similar 10 cc syringes marked with labels A and B. Syringe A containing 1.5 mg / kg lidocaine diluted to 10 cc for spraying with nelaton catheter on the vocal c

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients over 18 years ASA 2-3 Uncontrolled blood pressure Patients who are candidate for elective surgery under general anesthesia with endotracheal tube

Exclusion criteria

Exclusion criteria: Patients who are hypersensitive to any of the drugs lidocaine or remifentanil Patients who need rapid sequence induction Mallampati 3,4 Difficult intubation Consumption of beta blocker Patients who need to receive antihypertensive medication due to a significant increase in blood pressure during surgery

Design outcomes

Primary

MeasureTime frame
Blood pressure. Timepoint: After endotracheal intubation and after removal. Method of measurement: monitoring.;Heart rate changes. Timepoint: After endotracheal intubation and after removal. Method of measurement: monitoring.;?????? ????. Timepoint: After endotracheal intubation and after removal. Method of measurement: monitoring.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNushin Reza Alizadeh

Shiraz University of Medical Sciences

nushin.alizadeh@gmail.com+98 71 3647 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026