Comparison between local administration of magnesium sulfate and bupivacaine at trocar incision site in surgeries for laparoscopic cholecystectomy regarding their postoperative analgesic effects

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20141009019470N113

Enrollment

Registered

2021-04-03

Start date

2021-04-18

Completion date

Unknown

Last updated

2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cholecystectomy. Retained cholelithiasis following cholecystectomy

Interventions

Intervention 1: Intervention group: Bupivacaine 0.25% is prepared in a total amount of 1 mg / kg body weight and its total volume is increased to 60 cc with normal saline. All patients in both groups

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age 18-60 years PS ASA I, II Patients undergoing elective laparoscopic cholecystectomy

Exclusion criteria

Exclusion criteria: Pregnant or lactating women History of allergy to topical injections History of severe heart, respiratory and kidney disease Opium addicted patients People who have recently received strong analgesic drugs Incidence of the disease in the form of cholecystitis Patients who suffer from complications of anesthesia or surgery during the operation Patients who eventually undergo laparotomy

Design outcomes

Primary

Measure	Time frame
Severity of Pain. Timepoint: 1, 2, 6 hours after surgery. Method of measurement: Visual Analogue Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Mehrdadi

Shiraz University of Medical Sciences

mehrdadia@yahoo.com+98 71 3647 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026