The Efficacy of Tranexamic Acid and the Association of Rate Pressure Product Index on Intraoperative Bleeding during Rhinoplasty.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20141009019470N109

Enrollment

Registered

2021-02-08

Start date

2021-02-17

Completion date

Unknown

Last updated

2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rhinoplasty surgery. Encounter for cosmetic surgery

Interventions

Intervention 1: Intervention group: patients received 1gr Tranexamic acid intraoperatively (total volume of 10 cc). Intervention 2: Control group: patients received the same volume of Tranexamic acid

Eligibility

Sex/Gender

All

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 18-45 year_ old patients undergoing rhinoplasty surgery.

Exclusion criteria

Exclusion criteria: Patients with systemic disease History of any drug consumption Hemorrhagic disease Liver dysfunction Renal dysfunction Using anticoagulant drugs Heart block Myocardial ischemia Morbid obesity

Design outcomes

Primary

Measure	Time frame
Intra and postoperative bleeding. Timepoint: Intra-operatively. Method of measurement: Weighing surgical gauzes using a digital scale.;The rate-pressure product (RPP). Timepoint: Every 10 min. Method of measurement: Formula: heart rate multiply systolic arterial pressure.	—

Secondary

Measure	Time frame
Blood pressure. Timepoint: In the recovery room for the first 6. Method of measurement: Noninvasive blood pressure monitoring.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactForogh Moradi

Shiraz University of Medical Sciences

forooghmoradi.fm.67@gmail.com+98 71 3647 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026