Skip to content

Comparison of the efficacy of prophylactic ondansetron and ephedrine on hypotension associated with spinal anesthesia in cesarean section

Comparison of the efficacy of prophylactic ondansetron and ephedrine on hypotension associated with spinal anesthesia in cesarean section

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20141009019470N106
Enrollment
180
Registered
2021-01-26
Start date
2021-02-02
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cesarean. Encounter for cesarean delivery without indication

Interventions

Intervention 1: Intervention group one: patients will receive Ephedrine (Aterop, Belgium) 10 mg , during 5 minutes before spinal anesthesia . Intervention 2: Intervention group two: patients will rece

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age 18 years Elective cesarean section ASA classification I-II Term and singleton pregnancy

Exclusion criteria

Exclusion criteria: DM Hypertensive disorder Body Mass Index 40 Complicated pregnancy such as placenta Previa, preeclampsia History of Long QT syndrome History of Electrolyte imbalance Contraindication to spinal anesthesia Failed spinal block or total spinal converted to general anesthesia History of allergy to or side effects to the study drugs.

Design outcomes

Primary

MeasureTime frame
Hemodynamic data (SBP, DBP, MAP, HR, and SaO2). Timepoint: During Operation. Method of measurement: Manitoring.

Secondary

MeasureTime frame
Duration of motor block. Timepoint: 7 and 15 min after intrathecal injection. Method of measurement: Bromage scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactParnian Baghban

Shiraz University of Medical Sciences

parnianbaghban69@gmail.com+98 71 3647 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026