Comparison of the effects of spinal injection drugs on the duration of spinal anesthesia, complications and effect of spinal anesthesia in cesarean section

Comparing the intrathecal effects of sufentanil, fentanyl, and intravenous apotel as adjuvants to bupivacaine on duration, side effects, and efficiency of spinal anesthesia in elective cesarean section

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20141009019470N101

Enrollment

105

Registered

2020-07-28

Start date

2020-08-02

Completion date

Unknown

Last updated

2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cesarean section. Encounter for cesarean delivery without indication

Interventions

Intervention 1: Intervention group1:patients received 10 mg bupivacaine 0.5%, 2 micrograms of sufentanil, 0.1 ml of normal saline , and 200 cc normal saline as placebo intravenously after the umbilic

Eligibility

Sex/Gender

Female

Age

20 Years to 30 Years

Inclusion criteria

Inclusion criteria: Term pregnancy Age 20 to 30 years Weight 50 - 100 kg Height between 150 -180 cm ASA I-II Elective cesarean section

Exclusion criteria

Exclusion criteria: Patient refusal Localized infection in the lumbar region Use of anti platelet and anticoagulant Allergy to the local anesthetics Addiction to narcotics and nicotine Hypovolemic shock Diabetes Renal failure Coagulation disorder Liver disease Heart diseases History of seizures or any neurological disease, Hypertension Preeclampsia Fetal anomaly, (IUGR), improper growth of the fetus in the uterus, Hemoglobin less than 8, Multiple pregnancies, Non- vertex position

Design outcomes

Primary

Measure	Time frame
Sensory Block. Timepoint: Duration of sensory block. Method of measurement: pin-prick.;Motor block. Timepoint: Duration of motor block. Method of measurement: modified Bromage Scale.;Pain. Timepoint: Postoperative. Method of measurement: visual analog score.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReza Jouybar

Shiraz University of Medical Sciences

joybarr@sums.ac.ir+98 71 3647 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026