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The effect of Dexmedetomidine on Quality of Recovery after simple mastectomy under General anesthesia

The effect of Dexmedetomidine on Quality of Recovery after simple mastectomy under General anesthesia

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20141009019470N100
Enrollment
110
Registered
2020-07-18
Start date
2020-08-10
Completion date
Unknown
Last updated
2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mastectomy. Encounter for breast reconstruction following mastectomy

Interventions

Intervention 1: Intervention group:30 minutes before surgery, dexmedetomidine infusion will start at a dose of 0.4 mcg / kg. Intervention 2: Control group:The 0.9% normal saline infusion will start a

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
25 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients undergoing simple mastectomy surgery Age 25-65 years ASA Class I – II

Exclusion criteria

Exclusion criteria: History of heart failure History of Kidney Failure History of liver failure Psychiatric and cognitive disorders Chronic pain Drug abuse or using psychotropic drugs Pregnancy Alcohol abuse Long-term use of painkillers History of allergy to dexmedetomidine Redo surgery History of motor disease

Design outcomes

Primary

MeasureTime frame
The agitation. Timepoint: It is examined every 30 minutes for 2 hours in recovery as well as after the patient is transferred to ward every 2 to 6 hours. Method of measurement: Ramsay criteria.;Nausea and vomiting. Timepoint: It is examined every 30 minutes for 2 hours in recovery as well as after the patient is transferred to ward every 2 to 6 hours. Method of measurement: Likert.;Postoperative pain. Timepoint: It is examined every 30 minutes for 2 hours in recovery as well as after the patient is transferred to ward every 2 to 6 hours. Method of measurement: Visual analogue scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAyda Najafi Kashkooli

Shiraz University of Medical Sciences

ida_najafi@yahoo.com+98 71 3647 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026