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Comparison of ovulation induction by GnRH antagonist (Cetrotide) in patients with poor ovarian response with the previous ART(Assisted Reproductive Technology) cycles

Comparison of ovulation induction by GnRH antagonist (Cetrotide) in patients with poor ovarian response with the previous ART(Assisted Reproductive Technology) cycles

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014100819464N1
Enrollment
40
Registered
2014-11-19
Start date
2013-05-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Poor ovarian Responders. Other ovarian dysfunction

Interventions

Intervention 1: Intervention: Antagonist regimen ( Fustimone 300 unites daily after third day and vaginal sonography after ninth day of cycle are initiated. When 14mm follicle can be seen Cetrotide (0
Treatment - Drugs
Intervention: Antagonist regimen ( Fustimone 300 unites daily after third day and vaginal sonography after ninth day of cycle are initiated. When 14mm follicle can be seen Cetrotide (0.1mg/day) will b
Control: according to previous AVF method performed and documented in medical records of patient

Sponsors

Vice chancellor for research, Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Inclusion criteria: history of poor response to stimulation (10 mIU/ml, antral follicle count <5. Exclusion criteria: endometriosis,only one ovary, endocrine or metabolic disorder.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pregnancy. Timepoint: 7-6 weeks after intervention. Method of measurement: Ultrasound.

Secondary

MeasureTime frame
Endometrial thickness. Timepoint: Day of HCG injection. Method of measurement: Ultrasound.;Estradiol levels. Timepoint: Day of HCG injection. Method of measurement: Ultrasound.;The number of oocytes recovered. Timepoint: Day puncture. Method of measurement: Laboratory.;No. of fertilized oocytes. Timepoint: Day of embryo transfer. Method of measurement: Laboratory.;The amount of transferred embryos. Timepoint: Day of embryo transfer. Method of measurement: Laboratory.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSonia Ahmadi

Kerman University of Medical Sciences

soni.ahmadi@yahoo.com+98 34 1223 5011

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026