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Comparison the Effects of Intrathecal Meperidine and Dexmedetomidine added to Bupivacaine in the Woman Undergoing Cesarean Section.

Comparison the Effects of Intrathecal Dexmedetomidine and Meperidine as Adjuvants to Bupivacaine 0.5% in the Woman Undergoing Elective Cesarean Section

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014100814372N4
Enrollment
90
Registered
2015-02-02
Start date
2014-03-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cesarean. Delivery by elective caesarean section

Interventions

Intervention 1: Patients in placebo group received 0.5% bupivacaine (10 mg) and 0.5 mL of normal saline without preservative (total volume 2.5 ml) for spinal anesthesia. Intervention 2: Patients in in
Placebo
Treatment - Drugs
Patients in placebo group received 0.5% bupivacaine (10 mg) and 0.5 mL of normal saline without preservative (total volume 2.5 ml) for spinal anesthesia.
Patients in intervention group 1 received 0.5% bupivacaine (10 mg) and dexmedetomidine 5 micrograms (Origin orion pharma Germany) (total volume 2.5 ml) for spinal anesthesia.
Patients in intervention group 2 received 0.5% bupivacaine (10 mg) and 10 mg of meperidine (total volume 2.5 ml) for spinal anesthesia.

Sponsors

Shiraz University of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
15 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: pregnant women ASA I-II; singleton pregnancies; elective Caesarean section; term neonate; no contraindication for spinal anesthesia. Exclusion criteria :heart diseases; liver diseases; renal failure; coagulopathy; sensitivity to drugs; lack of consent; spinal anesthesia contraindication;a history of seizures; neurological diseases;(IUGR)

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
The duration of sensory block. Timepoint: Perioperative every 20 min and Post-operative 10 min after arrival to the recovery room. Method of measurement: Pinprick.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Zarghami

Shiraz University of Medical Sciences

zarghamiamir@sums.ac.ir+98 71 3235 7282

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026