Depression. In typical mild, moderate, or severe depressive episodes, the patient suffers from lowering of mood, reduction of energy, and decrease in activity.
Conditions
Interventions
Intervention 1: Soft gelatin Cap of omega-3 (Cap 1000 mg, Zahravi Pharmaceutical Company, Tabriz, Iran), One Cap orally twice daily, for 8 weeks. Intervention 2: Soft gelatin Cap of Placebo (Cap 1000m
Treatment - Drugs
Placebo
Soft gelatin Cap of omega-3 (Cap 1000 mg, Zahravi Pharmaceutical Company, Tabriz, Iran), One Cap orally twice daily, for 8 weeks
Soft gelatin Cap of Placebo (Cap 1000mg, Zahravi Pharmaceutical Company, Tabriz, Iran), One Cap orally twice daily, for 8 weeks.
Sponsors
Vice Chancellor for Research, Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: HIV positive patients with age between 18-65 years old, received antiretroviral therapy for at-least one years, CD4 count=350 and Beck Depression Score (BDS)=16. Exclusion criteria: HIV positive patients suffering from other psychological disorders, major depression with recent suicidal attempt, history of drugs or alcohol abuse, other concomitant severe medical diseases such as diabetes mellitus, intake of omega-3 during last 3 months, sensitivity to omega-3, coagulation disorders or intake of anticoagulants and receiving any drugs that affect patients’ mood including anti-depressants.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Beck depression score. Timepoint: at baseline, weeks 4 and 8. Method of measurement: Beck Depression Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Outcome results
None listed