blood transfusion in multiple trauma patient. Traumatic secondary and recurrent haemorrhage
Conditions
Interventions
Intervention 1: Intra venous transfusion of recombinant erythropoitin as 300 unit per Kg of patiant's weight in two minutes duration slowly under cardiac & respiratory monitoring in intervention grou
Treatment - Drugs
Intra venous transfusion of recombinant erythropoitin as 300 unit per Kg of patiant's weight in two minutes duration slowly under cardiac & respiratory monitoring in intervention group as a single do
would not be done in control group
Sponsors
Vice Chancellor for Research
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: inclusion criteria:being Multiple Trauma, age more than18 years, blood transfusion within 24 hours of enterance to the hospital, consiouss agreement of the patient (if has ability to decide & is completely alert) or his legal attendant/ deputy(in other situations),no affection to other diseases exclusion criteria: consiouss disagreement of the patient or his legal attendant/ deputy during the research,death of patient within first three days of hospital admission
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood transfusion volume to the patient. Timepoint: end of patient admission at the hospital. Method of measurement: number of pack cells with counting the documented transfused pack cells in patients' files.;Blood pressure. Timepoint: at the begining & third day of trial. Method of measurement: mm Hg with using mercury sphingomanometer set.;Heart beats. Timepoint: at the begining & third day of trial. Method of measurement: number of heart beats per minute with using heart monitoring set.;Blood oxygen saturation. Timepoint: at the begining & third day of trial. Method of measurement: percent of blood oxygen saturation with using pulse oximeter set.;Respiratory rate. Timepoint: at the begining & third day of trial. Method of measurement: number of patient's breath per minute with physical examination.;Plasma hepcidin. Timepoint: third day of trial. Method of measurement: nanogram per mililiter with using elisa technique.;Urine microalbumine to creatinine ratio. Timepoint: third day of trial. Method of measurement: miligram on milimoll with using radiimmunoassay & Jaffe techniques respectively. | — |
Secondary
| Measure | Time frame |
|---|---|
| Stay lenghth of patient in hospital. Timepoint: end of patient's admission in hospital. Method of measurement: number of admission days of patient in hospital with using formula discharge date minus admission date plus one.;Patiant's hotelling price in hospital. Timepoint: end of patient's admission in hospital. Method of measurement: price documented in patiant's echonomic file in Rials. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAli Mannani
Iran University of Medical Science
Outcome results
None listed