Condition 1: Irritable bowel syndrome. Condition 2: Constipation. Condition 3: Functional diarrhoea. Condition 4: Fissure and fistula of anal and rectal regions. Condition 5: Abscess of anal and rectal regions. Condition 6: Other diseases of anus and rectum. Condition 7: Other diseases of intestine. Condition 8: Other specified diseases of digestive system. Condition 9: Disease of digestive system, unspecified. Irritable bowel syndrome Constipation Functional diarrhoea Fissure and fistula of
Conditions
Interventions
Intervention 1: First intervention group: First intervention group treatment is carried out via Glycyrrhiza glabra (3 capsule D-reglis: 650mg per day) during 4 weeks. Intervention 2: Control group: In
Treatment - Drugs
Placebo
First intervention group: First intervention group treatment is carried out via Glycyrrhiza glabra (3 capsule D-reglis: 650mg per day) during 4 weeks.
Control group: In control group, placebo is utilized (3 capsule starches per day) during 4 weeks.
Second intervention group: Second intervention group treatment is carried out via Zataria multiflora (3 capsule gastrolit: 20 mg per day) during 4 week.
Sponsors
Vice Chancellor for Research of Arak University of Medical Science
Eligibility
Sex/Gender
All
Age
20 Years to 55 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: To be eligible for this trial, each volunteer needs to meet the following criteria at a screening and baseline visit: Volunteers between 20 to 55 years old, male or female, capable of giving informed consent, to have at least 1 year record of service in intensive care unit, and affected by gastrointestinal disturbances during the last weak. Exclusion criteria: Nonconformity with medication regimen, being affected by any severe systemic diseases. Moreover, volunteers that are receiving any medical treatment of stress induced symptoms (such as sleeping pills, antidepressants, or anxiolytics) or those who have taken such treatment since 3 months ago or later are also excluded. In addition, those volunteers who are using nicotine or who have weaned since 6 months ago are excluded.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Abdominal pain. Timepoint: 4 weeks. Method of measurement: Questionnaire.;Pyrosis. Timepoint: 4 weeks. Method of measurement: Questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in bowel habits (Constipation, Diarrhea). Timepoint: 4 Weeks. Method of measurement: Questionnaire.;Reflux. Timepoint: 4 Weeks. Method of measurement: Questionnaire.;Flatulence. Timepoint: 4 Weeks. Method of measurement: Questionnaire.;Xerostomia. Timepoint: 4 Weeks. Method of measurement: Questionnaire.;Vomiting. Timepoint: 4 Weeks. Method of measurement: Questionnaire.;Abdominal pain caused by hunger. Timepoint: 4 Weeks. Method of measurement: Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Sharareh Khosravi
Arak university of medical science
Outcome results
None listed