The effect of Utrica dioica extract on Glucose level and AMPK (Adenosine Monophosphate Activated Protein Kinase)enzyme

the effect ofHydroalcholic aerial parts of Utrica dioica extract on Glucose level and AMPK enzyme in type 2 diabetic patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014100119364N1

Enrollment

Registered

2015-02-15

Start date

2014-12-06

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type 2 diabet. Non-insulin-dependent diabetes mellitus type 2

Interventions

Intervention 1: Intervention:drug (HydroAlcholic Utrica dioica Extract) Intervention group (Taking usual diabetes medicines that donot have effect on AMPK level) ingest 20mg/kg of nettle extract 3 tim

Treatment - Drugs

Placebo

Intervention:drug (HydroAlcholic Utrica dioica Extract) Intervention group (Taking usual diabetes medicines that donot have effect on AMPK level) ingest 20mg/kg of nettle extract 3 time a day for 8 w

Control:placebo Control group(Taking usual diabetes medicines that donot have effect on AMPK level) ingest 20mg/kg of placebo 3 times a day for 8 weeks.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: Fasting blood sugar between110- 200 mg/dl; Taking usual diabetes medicines that donot have effect on AMPK enzyme level like metformin and thiazolidinediones; Exclusion criteria:Illness background kidney; cardiovascular; liver. Taking usual diabetes medicines that have effect on AMPK enzyame level like metformin and thiazolidinediones; Pregnancy and Lactating; insulin injection; Smoking and use of alcohol; change in diet and exercise.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
AMPK (Adenosine Monophosphate Activated Protein Kinaseenzme level. Timepoint: Befor & after intervention. Method of measurement: Immune assay.;Glucose blood level. Timepoint: befor & after intervention. Method of measurement: spectrophotometric assay(kit).	—

Secondary

Measure	Time frame
Hb A1C. Timepoint: Before & after intervention. Method of measurement: Spectrophotometric assay (kit).;Insulin. Timepoint: Before & after intervention. Method of measurement: Immune assay.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBahare Korani

Babol University of Medical Sciences

bahar_korani@yahoo.com+98 83 3432 8876

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026