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Comparison of the effectiveness of Pregabalin with Pregabalin-Paracetamol on postoperative pain

Comparison of the effectiveness of Pregabalin with Pregabalin-Paracetamol on postoperative pain Lumbar discectomy surgery; A Randomized clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20141001019359N17
Enrollment
60
Registered
2023-04-19
Start date
2023-03-07
Completion date
Unknown
Last updated
2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain. Other acute postprocedural pain

Interventions

Intervention 1: Intervention group1 : The intervention will be one hour before the operation, receive a single dose of 300 mg Pregabalin orally and 100 cc of 0.9% normal saline by infusion 30 minutes

Sponsors

Bojnourd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age between 20 to 60 years ASA physical status I-II Do not have drug addiction Do not have allergic to Pregabalin and Paracetamol

Exclusion criteria

Exclusion criteria: If the patient have used paracetamol or pregabalin 48 hours before the operation. If the patient be suffering from neurological and psychological, heart, lung, kidney and liver disease. If the patient has any history of epilepsy.

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: Recovery, 12, 24 and 48 hours after surgery. Method of measurement: Visual Analog Score (VAS) Form of pain.

Secondary

MeasureTime frame
Pregabalin and Paracetamol Side Effects. Timepoint: Up to 48 hours after surgery. Method of measurement: Examination and observation of the patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactJavad Shahinfar

Bojnourd University of Medical Sciences

dr.jshahinfar@gmail.com+98 58 3229 6966

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026