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Pregabalin and Paracetamol effect on pain after Laparoscopic cholecystectomy

The effect of pregabalin-paracetamol on shoulder pain in patients after laparoscopic cholecystectomy, Double-blind controlled randomized trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20141001019359N11
Enrollment
90
Registered
2022-01-09
Start date
2021-12-22
Completion date
Unknown
Last updated
2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain. Pain, not elsewhere classified

Interventions

Intervention 1: Intervention group: Administration One hour before surgery, a single dose of pregabalin 300 mg orally. And 30 minutes before the end of surgery Paracetamol 1 gr per 100cc of normal sal

Sponsors

Bojnourd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: 20 to 60 years ASA physical status I-II No drug addiction No disease with chronic pain No hypersensitivity to Pregabalin and Paracetamol No history of disease and surgery in the shoulder and chest area and abdominal surgery

Exclusion criteria

Exclusion criteria: Conversion of laparoscopic surgery to laparotomy any complication that increases postoperative pain

Design outcomes

Primary

MeasureTime frame
Post Operative Pain. Timepoint: Assay of pain at 0, 2, 4, 6, 8, 12 and 24 hours after surgery. Method of measurement: Visual Analog Score (VAS) Form of pain.;Pethedine/Morphine Consumption. Timepoint: First 24 hours after surgery. Method of measurement: Pethidine/Morphine consumption doses.

Secondary

MeasureTime frame
Time of surgery. Timepoint: From induction of anesthesia time to extubation. Method of measurement: Time observation.;Pregabalin and Paracetamol Side Effects. Timepoint: First 24 hours after surgery. Method of measurement: Examination and observation of the patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHossein Zeraati

Bojnourd University of Medical Sciences

zeraatih@gmail.com+98 915 532 2857

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026