Effect of Desmopressin on bleeding after coronary artery bypass graft

Effect of Desmopressin on bleeding in coronary artery bypass graft surgery patients undergoing cardiopulmonary bypass pump with antiplatelet drugs

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201409304345N3

Enrollment

100

Registered

2014-12-02

Start date

2014-11-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complications of Coronary artery bypass grafting. Mechanical complication of coronary artery bypass and valve grafts

Interventions

Intervention 1: Intervention 1: Giving 10-40 microgram desmopressin as two drops before CABG and repeat it 6 hours later, after surgery, in ICU. Intervention 2: Intervention 2: Giving 10-40 microgram

Treatment - Drugs

Intervention 2: Giving 10-40 microgram normal saline as two drops before CABG and repeat it 6 hours later, after surgery, in ICU

Intervention 1: Giving 10-40 microgram desmopressin as two drops before CABG and repeat it 6 hours later, after surgery, in ICU

Eligibility

Sex/Gender

All

Age

30 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria: Candidate for CABG; antiplatelet drugs Exclusion criteria: Need to get an postoperative anticoagulation

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Blood transfusion. Timepoint: During 24 hours after surgery. Method of measurement: Hemoglobin less than 9 by Sysmex K1000.;Platelet transfusions. Timepoint: During the first 24 hours after surgery. Method of measurement: Based on the platelet less than 100000.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Mirmansouri

Guilan University of Medical Sciences

arcguilan1392@gmai.com+98 13 3331 0434

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026