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Effect of simultaneous injection of autologous fat with platelet-rich plasma on the fat thickness of the bladder neck and proximal urethra in women with stress urinary incontinence

Effect of simultaneous injection of autologous fat with platelet-rich plasma on the fat thickness of the bladder neck and proximal urethra in women with stress urinary incontinence: a before after clinical trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201409299014N41
Enrollment
23
Registered
2014-10-07
Start date
2013-01-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stress urinary incontinence. Stress incontinence

Interventions

Intervention 1: injection of 1 ml subcutaneous fat at the proximal of urethra at 3, 6, and 9 o'clock positions seven times plus injection of 0.5 ml platelet-rich plasma at the proximal of urethra at 3
Treatment - Drugs
injection of 1 ml subcutaneous fat at the proximal of urethra at 3, 6, and 9 o'clock positions seven times plus injection of 0.5 ml platelet-rich plasma at the proximal of urethra at 3, 6, and 9 o'clo
comparison with the patients' condition before intervention

Sponsors

Vice-chancellor for Research the Technology, Hamadan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: (a) having stress urinary incontinence; (b) female sex; (c) age of 20 to 80 years. Exclusion criteria: (a) presence of moderate to severe cystocele; (b) detrusor overactivity in urodynamic test; (c) history of ureteral surgery; (d) hypermobility of the ureter (more than 30 degrees); (e) obesity (BMI more than 30)

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Assessing the fat thickness of the bladder neck and proximal urethra in mm. Timepoint: before intervention and one week and 3 months later. Method of measurement: using MRI.

Secondary

MeasureTime frame
Assessing the urethra bleeding. Timepoint: one week after intervention. Method of measurement: with question form the patients.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Adel Eslami

Shahid Beheshti Hospital

poorolajal@umsha.ac.ir+98 81 3838 0705

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026