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Comparison of the effects of acarbose and metformin on ovulation induction success

A clinical trial to compare the effects of acarbose and metformin use on ovulation induction success in women with polycystic ovary syndrome

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014092912789N7
Enrollment
60
Registered
2014-11-05
Start date
2014-08-06
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

polycystic ovary syndrome. Polycystic ovarian syndrome

Interventions

Intervention 1: Intervention group receive acarbose 100 mg/day for 3 months. This method that in the first week they receive 1 tablet, second week two tablets and third week three tablets per day. Int
Treatment - Drugs
Intervention group receive acarbose 100 mg/day for 3 months. This method that in the first week they receive 1 tablet, second week two tablets and third week three tablets per day.
Control group receive metformin 500 mg/day for 3 months. This method that in the first week they receive 1 tablet, second week two tablets and third week three tablets per day.

Sponsors

Vice Chancellor for Research, Kurdistan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age 20-40 years, women with polycystic ovary syndrome diagnosed by the rotterdam consensus criteria. Exclusion criteria: Smoking, Cushing's syndrome, thyroid function disorders, androgen secreting tumors, patients with liver disease, kidney disease, heart disease, diabetes, and use of other drugs for polycystic ovary syndrome.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Hirsutism. Timepoint: Before intervention -Three months after intervention. Method of measurement: Using Feriedman and Galway Scale.;Fasting insulin serum level. Timepoint: Before intervention -Three months after intervention. Method of measurement: Elisa assays.;Fasting sugar serum level. Timepoint: Before intervention -Three months after intervention. Method of measurement: Enzyme.;Blood pressure. Timepoint: Before intervention -Three months after intervention. Method of measurement: Barometers.

Secondary

MeasureTime frame
Triglyceride serum level. Timepoint: Before intervention -Three months after intervention. Method of measurement: Serological test with Electro Komolynsans method.;Cholestrol serum level. Timepoint: Before intervention -Three months after intervention. Method of measurement: Serological test with Electro Komolynsans method.;LDL serum level. Timepoint: Before intervention -Three months after intervention. Method of measurement: Serological test with Electro Komolynsans method.;HDL serum level. Timepoint: Before intervention -Three months after intervention. Method of measurement: Serological test with Electro Komolynsans method.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSomaye Mohammadpour

Kurdistan University of Medical Sciences

mohamadjamshidi87@yahoo.com+98 87 3328 8119

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026