Menopausal hot flushes. Menopausal and female climacteric states
Conditions
Interventions
Intervention 1: The first group received fluoxetine 20 mg daily for 4 weeks. After completion of 4 weeks, treatment was interrupted and after two weeks for washout, patients received gabapentin 300 mg
Treatment - Drugs
The first group received fluoxetine 20 mg daily for 4 weeks. After completion of 4 weeks, treatment was interrupted and after two weeks for washout, patients received gabapentin 300 mg daily for anoth
The second group received gabapentin 300 mg daily for 4 weeks. After completion of 4 weeks, treatment was interrupted and after two weeks for washout, patients received fluoxetine 20 mg daily for anot
Sponsors
Vice chancellor for research? Semnan University of Medical Sciences
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Inclusion criteria: last period at least one year ago; having at least two hot flashes per day; starting of flashes has been at least four months; should not be used any drugs to treat hot flashes now and a month ago. Exclusion criteria: taking of multivitamin; anticoagulant drugs (eg: warfarin); chemotherapy drugs; thyroid disorders; hemophilia; immune deficiency; diabetes; hypertension and rheumatic heart disease.
Exclusion criteria
Exclusion criteria:
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Tremor. Timepoint: 4 weeks after initiation of treatment. Method of measurement: GREENE CLIMACTERIC SCALE.;Anorexia. Timepoint: 4 weeks after initiation of treatment. Method of measurement: GREENE CLIMACTERIC SCALE. | — |
Primary
| Measure | Time frame |
|---|---|
| Severity of hot flushing. Timepoint: 4 weeks after initiation of treatment. Method of measurement: GREENE CLIMACTERIC SCALE. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Mojgan Rahmanian
Semnan University of Medical Sciences
Outcome results
None listed